ANAHEIM, Calif. — Shohei Ohtani won’t pitch for the rest of the season because of a ligament tear in his right elbow, Los Angeles Angels general manager Perry Minasian said Wednesday night.

The Angels don’t yet know whether Ohtani will need surgery to repair the UCL ligament nearly five years after the two-way superstar first had Tommy John surgery.

“A tough day for him,” Minasian said. “Tough day for all of us.”

The injury will have a massive effect on baseball’s free agent market this winter with Ohtani headed to unrestricted free agency. The uniquely valuable American League MVP front-runner was expected to receive the most lucrative contract offers in baseball history after six landmark seasons with the Angels, but now much will depend on the health of his pitching elbow.

“If I was to bet on anybody bouncing back, he would be the guy,” said Minasian, who didn’t know the grade of Ohtani’s ligament tear.

The Angels also announced Wednesday night that three-time AL MVP Mike Trout will go back on the injured list. Trout, who sat out both games of the doubleheader after waking up sore, came off the injured list Tuesday after missing 38 games following surgery on a broken bone in his hand.

Ohtani is the major league leader with 44 homers after connecting in the first game of the doubleheader Wednesday. He has 10 wins with a 3.14 ERA on the mound.

Ohtani left the mound in the middle of an at-bat during the second inning, feeling what the Angels called arm fatigue. Postgame tests revealed Ohtani developed a ligament tear nearly five years after he had Tommy John surgery on his pitching elbow.

Ohtani, who homered in the first inning of the opener, told the Angels he wanted to play in the nightcap. Ohtani served as the Angels’ designated hitter for much of the 2019 season after having Tommy John surgery following his rookie stateside campaign in 2018.

Minasian said he isn’t sure whether his two-way superstar will continue to serve as their designated hitter.

“I think he needs time to wrap his head around it, talk to the people close to him,” Minasian said. “We’re in the process of getting second opinions. Once the information is there, he’ll make the right decision on what he wants to do, and we’ll support him, whatever he decides. … I wouldn’t be surprised if he’s in New York and he’s in the lineup. I know how bad he wants to play.”

Ohtani skipped his previous turn in the rotation last week to rest his arm late after a long summer. Ohtani’s velocity was down across the board Wednesday while he faced the Reds’ first six batters, although he sometimes ramps up his pitching speeds gradually in the opening innings.

Ohtani had a 2-2 count on Cincinnati Reds third baseman Christian Encarnacion-Strand when the Angels’ training staff came out to check on him following a 94 mph fastball. Ohtani headed off the mound after a brief discussion, having thrown just 26 pitches.

Angels manager Phil Nevin said Ohtani’s velocity was down in the second inning of his start in the opener.

“I was noticing the shapes on his pitches just weren’t the same, and I just saw a look after a pitch, so I decided to go out there and check on him,” Nevin said.

Ohtani is almost certain to win his second AL MVP award in three seasons after another standout two-way campaign. His two-run homer gave him 91 RBIs and broke his tie with Atlanta’s Matt Olson atop the homer standings.

Ohtani was back in the Angels’ lineup for the nightcap as their designated hitter. The two-way superstar has missed only two games all season, none since May 2.

Nevin said Ohtani told him that his pitching arm “just didn’t feel right.”

“He told me he didn’t feel any pain,” Nevin said after the Angels’ 9-4 loss. “It was just more of the same thing he’s been feeling for the last couple of weeks.”

Ohtani hit his major league-leading 44th homer in the first inning of the opening game, a two-run shot. He also left that game as the Angels’ designated hitter, with rookie Nolan Schanuel replacing him.

Ohtani has struggled with blisters, cramps and other minor injuries to his pitching hand, but he had pitched through them while continuing to play every day at DH, including in three straight starts earlier this summer where he pitched at least five innings each time. He then left the mound after four scoreless innings against Seattle on Aug. 3 because of cramping in his hand and fingers. Ohtani has rarely let pitching injuries stop him from hitting for the Angels, even playing 106 games in 2019 as the Angels’ DH while he was recovering from Tommy John surgery.

The Associated Press contributed to this report.